Plot:After a long journey, Philip arrives at the Usher mansion seeking his loved one, Madeline. Upon arriving, however, he discovers that Madeline and her brother Roderick Usher have been afflicted with a mysterious malady: Roderick's senses have become painfully acute, while Madeline has become catatonic. That evening, Roderick tells his guest of an old Usher family curse: any time there has been more than one Usher child, all of the siblings have gone insane and died horrible deaths. As the days wear on, the effects of the curse reach their terrifying climax.

Plot:Two horror segments based on Edgar Allan Poe stories set in and around the city of Pittsburgh. "The Facts in the Case of M. Valdemar" concerns a cheating wife who is trying to scam her dying husband out of millions by having her doctor/hypnotist lover hypnotize the geezer into signing his dough over to her. The old man dies while under hypnosis and is stuck in the limbo between the here and the hereafter. The door to the physical world is opened and the undead attempt to enter it. "Black Cat" is the story of Rodd Usher, an alcoholic photographer/artist, who descends into madness after he kills a stray cat that his live-in girlfriend Annabelle brings home. One murder leads to another, and the complex cover-ups begin.

Plot:A man's recently transplanted heart leads him on a frantic search to find the donor's killer before a similar fate befalls him.